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Inflammation 1st set - slide 1
The burden associated with depression is large and increasing
References
  1. Ratnasingham S et al. Opening Eyes, Opening Minds: The Ontario Burden of Mental Illness and Addictions Report. Institute for Clinical Evaluative Sciences and Public Health Ontario, 2012
  2. Wittchen HU et al. Eur Neuropsychopharmacol 2011;21:655-79.
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Inflammation 1st set - slide 2
Depression is the most burdensome disorder of all brain diseases in the EU
The DALY is a health gap measure for the burden of disease, capturing both years of life lost due to premature mortality and years of life lost due to living with a disability. Overall, the burden of disease in mental and other disorders of the brain is mainly due to disa…
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Inflammation 1st set - slide 3
Depression has detrimental effects on overall health
References

Adapted from Moussavi S et al. Lancet. 2007;370:851-8.

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Inflammation 1st set - slide 4
Depression is associated with significant personal and societal consequences
References
  1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Health Disorders. 5th ed. Washington, DC: American Psychiatric Association; 2013
  2. Krol M, et al. Pharmacoeconomics. 2011;29(7):601–19
  3. Marcus M, et al. 2012.
    https://www.who.int/mental…
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Inflammation 1st set - slide 5
The personal burden of MDD can be significant and wide-ranging
References
  1. Kessler RC. Psychiatr Clin North Am 2012;35(1):1-14.

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Inflammation 1st set - slide 6
MDD has significant costs to society

!--?xml version="1.0" encoding="UTF-8" standalone="yes"?-- This slide illustrates the global social burden of MDD. The data are based on a systematic review of epidemiological data by Ferrari et al 2013. For this data were pooled using a Bayesian meta-regression. These we…

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Inflammation 1st set - slide 7
MDD has significant costs to society: EU

!--?xml version="1.0" encoding="UTF-8" standalone="yes"?-- This slides illustrates European burden of MDD with a focus on costs inferred due to impact on work.

Note that:
Absenteeism = lost days of work.
Presenteeism = low performance while at work, which is transformed in…

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Inflammation 1st set - slide 8
Depression is associated with significant economic costs
References
  1. Collins PY et al. Nature. 2011;475:27-30
  2. Sobocki P et al. J Ment Health Policy Econ. 2006;9:87-98
  3. Stewart WF et al. JAMA. 2003; 289:3135-44; 
  4. World Health Organization. Available at: https://www.who.int/healthinfo/global_burden_disease/GBD_report_2004update_pa…
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