Anxiety and panic disorder

In the HADAS study, the Mini International Neuropsychiatric Interview (MINI) was administered to people with migraine without aura (n=158) and people with tension-type headache or migraine plus tension-type headache (n=110; n=106 for migraine alone).^{[Beghi et al., 2010]} Of the people with migraine, the MINI detected anxiety in 18.4%, and panic disorder in 12.7%, compared with 19.3% and 5.5%, respectively, for people with tension-type headache.^{[Beghi et al., 2010]} A multivariate analysis found that people with migraine were at an almost three-times greater risk for panic disorder compared with people with tension-type headache with or without migraine.^{[Beghi et al., 2010]}

Reference:
Beghi E, Bussone G, D’Amico D, et al. Headache, anxiety and depressive disorders: the HADAS study. J Headache Pain 2010; 11 (2): 141–150.

Other references used on slide:
Antonaci F, Nappi G, Galli F, et al. Migraine and psychiatric comorbidity: a review of clinical findings. J Headache Pain 2011; 12 (2): 115–125.

Breslau N, Davis GC, Andreski P. Migraine, psychiatric disorders, and suicide attempts: an epidemiologic study of young adults. Psychiatry Res 1991; 37 (1): 11–23.

Buse DC, Manack A, Serrano D, et al. Sociodemographic and comorbidity profiles of chronic migraine and episodic migraine sufferers. J Neurol Neurosurg Psychiatry 2010; 81 (4): 428–432.

Smitherman TA, Kolivas ED, Bailey JR. Panic disorder and migraine: comorbidity, mechanisms, and clinical implications. Headache 2013; 53 (1): 23–45.