People with migraine appear to be at a greater risk of stroke than the general population, a risk which appears to increase with the frequency of migraine attacks.[Guidetti et al., 2014] Although the mechanisms underlying the comorbidity are not understood, people with migraine should be screened for modifiable vascular risk factors.[Guidetti et al., 2014; Dodick, 2009] Such risk factors include smoking, hypertension, diabetes, and hypercholesterolaemia.[Spalice et al., 2016] Many therapeutic options for migraine are vasoconstrictive agents, making consideration of migraine and CVD comorbidity all the more pertinent.[Spalice et al., 2016]
Other reference used on slide:
Mahmoud AN, Mentias A, Elgendy AY, et al. Migraine and the risk of cardiovascular and cerebrovascular events: a meta-analysis of 16 cohort studies including 1 152 407 subjects. BMJ Open 2018; 8: e020498.