An appreciation of the effect of migraine comorbidities on people with migraine, adding to the already burdensome condition, was part of the reason that the Migraine in America Symptoms and Treatment (MAST) study was undertaken.[Buse et al., 2020] By comparing a large sample of people with migraine (n=15,133) with control individuals (n=77,453), the MAST study highlighted the comorbidity burden of migraine, and used regression models to show that headache pain intensity and headache frequency were linked to an increased risk of various comorbidities.[Buse et al., 2020] As outlined on the slide, comorbidities can have a negative impact on the course of migraine.[Lantéri-Minet et al., 2011]
References:
Buse DC, Reed ML, Fanning KM, et al. Comorbid and co-occurring conditions in migraine and associated risk of increasing headache pain intensity and headache frequency: results of the Migraine in America Symptoms and Treatment (MAST) study. J Headache Pain 2020; 21 (1): 23.
Lantéri-Minet M, Duru G, Mudge M, Cottrell S. Quality of life impairment, disability and economic burden associated with chronic daily headache, focusing on chronic migraine with or without medication overuse: a systematic review. Cephalalgia 2011; 31 (7): 837–850.
Other references used on slide:
Galego JCB, Moraes AM, Cordeiro JA, Tognola WA. Chronic daily headache: stress and impact on the quality of life. Arq Neuropsiquiatr 2007; 65 (4B): 1126–1129.
Lipton RB, Hamelsky SW, Kolodner KB, et al. Migraine, quality of life, and depression: a population-based case-control study. Neurology 2000; 55 (5): 629–635.
Mercante JPP, Bernik MA, Zukerman-Guendler V, et al. Comorbidade psiquiátrica diminui a qualidade de vida de pacientes com enxaqueca crônica [Psychiatric comorbidities decrease quality of life in chronic migraine patients]. Arq Neuropsiquiatr 2007; 65 (3B): 880–884.
Page LA, Howard LM, Husain K, et al. Psychiatric morbidity and cognitive representations of illness in chronic daily headache. J Psychosom Res 2004; 57 (6): 549–555.
Wang SJ, Fuh JL, Lu SR, Juang KD. Quality of life differs among headache diagnoses: analysis of SF-36 survey in 901 headache patients. Pain 2001; 89 (2–3): 285–292.
