The slide shows a schematic of how cortical spreading depression might interact with the trigeminovascular system in one proposed model of migraine pathology.[Tolner et al., 2019] Of course, although the importance of the cortex in migraine is uncontroversial, there are many conflicting observations and experimental results in the field of migraine study that have yet to be satisfactorily integrated.[Tolner et al., 2019] This uncertainty highlights the importance of hypothesis-driven study designs in future experiments investigating migraine pathology.[Tolner et al., 2019]
A model of migraine pathophysiology
