The Parkinson Progression Marker Initiative (PPMI) is a comprehensive, observational, international study designed to identify PD progression biomarkers.2,4 The aim of the study is to improve the understanding of the causes of PD, and to provide tools to enhance future clinical trials of potential therapies.2,4

 

References:
1.The Parkinson’s Progression Markers Initiative (PPMI). Study Protocol. October 2015.

2.PPMI website. PPMI-info.org. Accessed January 2025.

3.Marek K, Chowdhury S, Siderowf A, et al.; Parkinson’s progression markers initiative. The Parkinson’s progression markers initiative (PPMI) – establishing a PD biomarker cohort. Ann Clin Transl Neurol 2018; 5 (12): 1460–1477.

4.Parkinson Progression Marker Initiative. The Parkinson Progression Marker Initiative (PPMI). Prog Neurobiol 2011; 95 (4): 629–635.