SynNeurGe – biological classification of Parkinson’s disease

In 2024 The Lancet Neurology published two competing biological frameworks that were proposed to move the diagnosis of Parkinson’s disease beyond the presence of a combination of cardinal motor signs and symptoms.² One of these was the SynNeurGe system, as summarised on the slide.¹

References:
1.Höglinger GU, Adler CH, Berg D, et al. A biological classification of Parkinson’s disease: the SynNeurGe research diagnostic criteria. Lancet Neurol 2024; 23 (2): 191–204.

2.Darweesh SKL, Sampaio C, Bloem BR. Has the time come to redefine Parkinson’s disease? Lancet Neurol 2024; 23 (2): 130–133.