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  • Schizophrenia – Aetiology and neurobiology
  • How do risk factors in the development of schizophrenia interact?

How do risk factors in the development of schizophrenia interact?

Schizophrenia
Slide illustrating how genetic and environmental risk factors may interact to contribute to schizophrenia and psychosis risk.

References:
1. McCutcheon RA, Reis Marques T, Howes, OD. Schizophrenia-an overview. JAMA psychiatry 2020; 77: 201–210.
2. Jauhar S, Johnstone M, McKenna PJ. Schizophrenia. Lancet 2022; 399: 473–486.
3. Leucht S, Siafis S, McGrath JJ, et al. Schizophrenia. Nat Rev Dis Primers 2025; 11: 83.
4. Jones HJ, Hammerton G, McCloud T, et al. Examining pathways between genetic liability for schizophrenia and patterns of tobacco and cannabis use in adolescence. Psychol Med 2022; 52: 132‒139.
5. Selten JP, Di Forti M, Quattrone D, et al. The contribution of cannabis use to the increased psychosis risk among minority ethnic groups in Europe. Psychol Med 2024; 54: 2937‒2946.
6. Laurens KR, Luo L, Matheson SL, et al. Common or distinct pathways to psychosis? A systematic review of evidence from prospective studies for developmental risk factors and antecedents of the schizophrenia spectrum disorders and affective psychoses. BMC Psychiatry 2015; 15: 205.

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Published 23.06.2026
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