The following slides review key neurobiological hypotheses, before examining an emerging integrative model that links these mechanisms together to explain the symptoms of schizophrenia.
References:
1. Howes OD, Cummings C, Chapman GE et al. Neuroimaging in schizophrenia: an overview of findings and their implications for synaptic changes. Neuropsychopharmacology 2023; 48: 151–167.
2. Leucht S, Siafis S, McGrath JJ, et al. Schizophrenia. Nat Rev Dis Primers 2025; 11: 83.