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  • Schizophrenia – Aetiology and neurobiology
  • Summary of aetiology and neurobiology of schizophrenia

Summary of aetiology and neurobiology of schizophrenia

Schizophrenia
Slide summarizing key genetic, environmental, and neurobiological factors implicated in schizophrenia.

References:
1. de Bartolomeis A, Barone A, Vellucci L, et al. Linking inflammation, aberrant glutamate-dopamine interaction, and post-synaptic changes: translational relevance for schizophrenia and antipsychotic treatment: a systematic review. Mol Neurobiol 2022; 59: 6460–6501.
2. Howes OD, Onwordi EC. The synaptic hypothesis of schizophrenia version III: a master mechanism. Mol Psychiatry 2023; 28: 1843–1856.
3. Howes OD, Shatalina E. Integrating the neurodevelopmental and dopamine hypotheses of schizophrenia and the role of cortical excitation-inhibition balance. Biol Psychiatry 2022; 92: 501–513.
4. Howes OD, Bukala BR, Beck K. Schizophrenia: from neurochemistry to circuits, symptoms and treatments. Nat Rev Neurol 2024; 20: 22–35.

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Published 23.06.2026
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