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  • Schizophrenia – Course, Natural History and Prognosis
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Trauma, social cognition, and functioning

Schizophrenia
Slide showing associations between childhood trauma, social cognition, and functional outcomes in psychotic disorders

The colour and thickness of the lines indicate the strength of the evidence: darker, thicker lines represent strong evidence (n ≥ 5), while lighter, thinner lines represent emerging evidence (n = 1).2 Dotted lines and grey text indicate areas where evidence is lacking and further research is needed.2

References:
1. Alameda L, Christy A, Rodriguez V, et al. Association between specific childhood adversities and symptom dimensions in people with psychosis: systematic review and meta-analysis. Schizophr Bull 2021; 47: 975–985.
2. Fares-Otero N, Alameda L, Paltz, et al. Examining associations, moderators and mediators between childhood maltreatment, social functioning, and social cognition in psychotic disorders: a systematic review and meta-analysis. Psychol Med 2023; 53: 5909–5932.
3. Mansueto G, Schruers K, Cosci F, et al. Childhood adversities and psychotic symptoms: The potential mediating or moderating role of neurocognition and social cognition. Schizophrenia Research 2019; 206: 183–193.

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Published 08.06.2026
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