Notable differences in all-cause, suicide-related, and specific-cause mortality risk have been observed across different regions.1 While mortality risk varies across regions, it is important to note that most data comes from North America, and Western and Northern Europe. Limited data are available for Central and South America, Eastern Europe, the Middle East and South Eastern Asia,1 meaning the mortality risk is not accurately captured for these regions.
References:
1.Solmi M, Croatto G, Fornaro M, et al. Regional differences in mortality risk and in attenuating or aggravating factors in schizophrenia: a systematic review and meta-analysis. Eur Neuropsychopharmacol 2024; 80: 55–69.
2.Correll CU, Solmi M, Croatto G, et al. Mortality in people with schizophrenia: a systematic review and meta-analysis of relative risk and aggravating or attenuating factors. World Psychiatry 2022; 21: 248–271.
3.Solmi M, Firth J, Miola A, et al. Disparities in cancer screening in people with mental illness across the world versus the general population: prevalence and comparative meta-analysis including 4 717 839 people. Lancet Psych 2020; 7: 52–63.
4.Solmi M, Fiedorowicz J, Poddighe L, et al. Disparities in screening and treatment of cardiovascular diseases in patients with mental disorders across the world: systematic review and meta-analysis of 47 observational studies. Am J Psychiatry 2021; 78: 793–803.
5.Wagner E, Højlund M, Fiedorowicz JG, et al. Lancet Psych 2026; 13: 112–124.
