The GBD study has quantified the burden of 371 diseases, including schizophrenia, across 204 countries and territories, using metrics such as ‘years lived with a disability’, ‘disability-adjusted life-years’, ‘years of life lost to premature mortality’, and ‘healthy life expectancy’, alongside prevalence and incidence.1,3
GBD estimates are partially based on incomplete data and statistical modelling, so they must be interpreted with caution; however, it remains the most comprehensive source available, providing useful insights.1,3
Abbreviation: GBD=Global Burden of Diseases
References:
1.GBD 2019 Mental Disorders Collaborators. Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Psychiatry 2022; 9: 137–150.
2.Solmi M, Seitidis G, Mavridis D, et al. Incidence, prevalence, and global burden of schizophrenia – data, with critical appraisal, from the Global Burden of Disease (GBD) 2019. Mol Psychiatry 2023; 28: 5319–5327.
3.GBD 2021 Diseases and Injuries Collaborators. Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet 2024; 403: 2133–2161.
4.Solmi M, Radua J, Olivola M, et al. Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies. Mol Psychiatry 2022; 27 (1): 281–295.
