Genes known to be associated with Parkinson’s disease

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Table showing genes linked to Parkinson’s disease, with inheritance patterns, clinical phenotypes, and gene functions like mitochondrial or lysosomal roles.

Since the discovery of SNCA, several genes have been found that can cause PD^1,²
Studies of families with high rates of PD, as well as twin studies, have been used to identify genetic factors that contribute to the development of PD, including monogenic causes^1,²

SNCA=α-synuclein; PD=Parkinson’s disease

Access Slide Deck: Parkinson’s disease – Neurobiology and aetiology

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