The thalamus is the largest part of the four main subdivisions of the diencephalon, it consists of neurons that collectively project to nearly all areas of the cerebral cortex1. The vast majority of information that reaches the cerebral cortex is firstly processed within the thalamus. The thalamus is therefore termed ‘the functional gateway to the cerebral cortex’. In turn nearly all regions of the cerebral cortex give rise to reciprocal projections that return to the thalamic region from which they originally received input1. Damage to the thalamus can lead to a variety of sensory and motor deficits, and can affect motor control, leading to movement disorders such as tremors or ataxia3,4

file_download Download in HQ

Related content

image Image A diagram showing how proprioception operates through sensory feedback
Proprioception and sensory feedback

Controlled movement relies on sensory feedback, particularly proprioception (the sense of body position in space and movement).

22.09.2026 Fundamentals of Neurobiology
image Image Diagram of the olfactory system showing odor detection in the nasal cavity and projections to brain regions.
The olfactory system

The olfactory system detects airborne odor molecules in the nasal cavity and transmits this information to the olfactory bulb. From there, signals are relayed to several brain regions involved in smell perception, memory, emotion, and behaviour.

02.06.2026 Fundamentals of Neurobiology
image Image Diagram of the gustatory pathway from the tongue to the gustatory cortex via brainstem and thalamic nuclei.
The gustatory (taste) system

The gustatory system detects taste stimuli on the tongue and relays this information through brainstem and thalamic pathways to the gustatory cortex.

02.06.2026 Fundamentals of Neurobiology