The burden of migraine

This systematic literature review incorporated information from 51 publications, and identified 34 ‘psychosocial difficulties’ associated with migraine, which were reported a total of 231 times across the included studies.^{[Raggi et al., 2012]} These psychosocial difficulties were categorised according to the World Health Organization’s International Classification of Functioning, Disability and Health (ICF) framework, using established methods.^{[Raggi et al., 2012]} As shown on the slide, the results highlighted the many burdensome psychosocial difficulties that are associated with migraine.^{[Raggi et al., 2012]}

There are patient-reported outcome (PRO) scales that can be used to assess the burden of migraine on an individual.^{[Haywood et al., 2018]} A review of PROs assessing the impact of headaches found 11 headache- or migraine-specific scales that measure patient impact.^{[Haywood et al., 2018]} Of these scales, the Migraine-Specific Quality of Life Questionnaire (MSQ) and the Headache Impact Test – 6-item (HIT-6) had the greatest evidence base.^{[Haywood et al., 2018]}

References:
Haywood KL, Mars TS, Potter R, Patel S, Matharu M, Underwood M. Assessing the impact of headaches and the outcomes of treatment: a systematic review of patient-reported outcome measures (PROMs). Cephalalgia 2018; 38 (7): 1374–1386.

Raggi A, Giovannetti AM, Quintas R, D’Amico D, Cieza A, Sabariego C, et al. A systematic review of the psychosocial difficulties relevant to patients with migraine. J Headache Pain 2012; 13 (8): 595–606.

Other reference used on slides:
Agosti R. Migraine burden of disease: from the patient’s experience to a socio-economic view. Headache 2018; 58 (Suppl 1): 17–32.

Buse DC, Fanning KM, Reed ML, et al. Life with migraine: effects on relationships, career, and finances from the Chronic Migraine Epidemiology and Outcomes (CaMEO) study. Headache 2019; 59 (8): 1286–1299.

Martelletti P, Schwedt TJ, Lanteri-Minet M, et al. My Migraine Voice survey: a global study of disease burden among individuals with migraine for whom preventive treatments have failed. J Headache Pain 2018; 19 (1): 115.

Smitherman TA, Burch R, Sheikh H, Loder E. The prevalence, impact, and treatment of migraine and severe headaches in the United States: a review of statistics from national surveillance studies. Headache 2013; 53 (3): 427–436.