Course trajectories over 2-, 4- and 6-year follow-upfor the different diagnostic categories

• Outcomes from depression can range from remission to chronic depression, switching to other psychiatric disorders, and death^1-3
• One large study followed 903 people with MDD at baseline over a course of 6 years¹
• Over 6-years of follow-up, recurrence of depression and chronic symptoms were the rule, rather than the exception – especially when the entire spectrum of affective disorder outcomes is considered^1,2
• Moreover, over time switching from MDD to other affective disorders (e.g., anxiety disorders, (hypo)manic disorder, or dysthymia) is common in people with baseline MDD¹

MDD=major depressive disorder