This was a randomized, double-blind, placebo-controlled study comparing fluoxetine, CBT, or a combination of both, in the treatment of generalized social phobia.
Over 14 weeks of treatment, the response rates for people receiving the various treatments were:
- Fluoxetine: 50.9%
- CBT: 51.7%
- CBT plus fluoxetine: 54.2%
- CBT plus placebo: 50.8%
- Placebo: 31.7%
Whilst all the active treatments studied performed significantly better than placebo, the combined treatment did not yield any further significant advantage.
CBT=cognitive–behavioural therapy; CCBT=comprehensive cognitive behavioural therapy; FLU=fluoxetine; PBO=placebo
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