Suicidal ideation is much more prevalent than suicide attempts among people with anxiety and/or depressive disorders.1 The most consistent determinants of suicidal ideation as well as suicide attempts were a diagnosis of comorbid depressive and anxiety disorder (compared with an anxiety disorder alone), and higher severity of depression.1
MDD=major depressive disorder; NESDA=Netherlands Study of Depression and Anxiety
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Decades of twin and family research have established that anxiety disorders run in families and are meaningfully influenced by genetic factors. Family and twin studies suggest an increased recurrence risk for first degree relatives of patients with anxiety to develop any anxiety disorders.
Family and twin studies estimate recurrence risk and heritability, showing that anxiety disorders aggregate in families and have a moderate genetic component.
