Schizophrenia is a highly heterogeneous disorder with variable onset, symptom patterns, and long-term outcomes.1,3 The onset of schizophrenia is thought to arise from the interaction between neurobiological vulnerability and environmental exposures during development.3,4
The disease course is often fluctuating, with episodic exacerbations and periods of remission.3 Recent data show substantially better outcomes than historically assumed.3
APS=attenuated psychotic symptoms; BLIPS=brief limited intermittent psychotic symptoms; FEP=first-episode psychosis
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Negative symptoms are a core feature of schizophrenia and can have a profound impact on functioning, social relationships, and quality of life.