The presence of psychiatric and physical comorbidities adversely affects health outcomes and general functioning and increases treatment costs and healthcare resource utilization in people with MDD.1,2 MDD comorbid with another medical disorder is also strongly associated with a reduction in the ability to work full-time, and with an increase in disability.2
MDD=major depressive disorder
Related content
Treatment-resistant depression (TRD) represents a significant clinical challenge, affecting approximately 30% of individuals with major depressive disorder (MDD) who fail to respond to at least two adequate antidepressant trials.
Sequential treatment optimization scheme for major depressive disorder generated according to international evidence.
Key steps for managing factors that may confound antidepressant treatment response, including dose, side effects, comorbidities, stressors, adherence, pharmacogenomics, interactions, and treatment algorithms.