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Perimenopause, Menopause, and Mental Health

Summary of the physiological changes associated with reproductive aging and the potential links between the menopausal transition and mental health conditions.

09.02.2026 Mental Health
image Image Sex hormone fluctuation and increased female risk for depression and anxiety disorders From clinical evidence to molecular mechanisms
Fluctuating ovarian hormones in women across lifespan

This illustration shows key phases of ovarian hormone fluctuation across the female lifespan, from menarche to menopause.

09.02.2026 Mental Health
image Image Figure illustrating endocrine changes during perimenopause
Physiological changes in the endocrine function during the perimenopause

Physiological changes in endocrine function from the reproductive stage to perimenopause

09.02.2026 Mental Health