According to the systematic analysis carried out for The Global Burden of Diseases, Injuries and Risk Factors Study in 2019, depressive disorders accounted for the greatest proportion of DALYs attributable to mental disorders, followed second by anxiety disorders (22.9% of all DALYs).
DALY=disability-adjusted life year; GBD=global burden of disease
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Decades of twin and family research have established that anxiety disorders run in families and are meaningfully influenced by genetic factors. Family and twin studies suggest an increased recurrence risk for first degree relatives of patients with anxiety to develop any anxiety disorders.
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