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image Image Bar chart displaying prevalence rates of major depressive disorder (MDD) by sex and age group, with females showing higher prevalence than males across most age brackets.
The global prevalence of MDD by sex and time

MDD is more prevalent in females, especially from adolescence onward.

22.07.2025 Depression
image Image Graph showing the clinical course of major depressive disorder, from no depression to acute symptoms, treatment response, remission, recovery, relapse, and recurrence.
Physical health outcome in people with depression

MDD follows a course with phases of response, remission, relapse, and recurrence.

22.07.2025 Depression
image Image Graph showing the clinical course of major depressive disorder, from no depression to acute symptoms, treatment response, remission, recovery, relapse, and recurrence.
The course of MDD

MDD follows a course with phases of response, remission, relapse, and recurrence.

22.07.2025 Depression
image Image Three pie charts showing MDD course trajectories over 2, 4, and 6 years, indicating reduced recovery rates and increased chronic episodes over time.
Course trajectories over 2-, 4- and 6-year follow-up for the different diagnostic categories

Longer follow-up shows reduced recovery rates in MDD.

22.07.2025 Depression
image Image Venn diagram showing the impact of depression symptoms on work/school, family/personal life, and social life, including issues like sick leave, interpersonal problems, and reduced autonomy.
The impact of the symptoms of depression on patients

Depressive symptoms affect work, family, and social life.

22.07.2025 Depression
image Image Venn diagram showing emotional, cognitive, and physical symptoms of depression, such as sadness, memory issues, fatigue, and sleep disturbances.
Symptoms of depression

Depression includes emotional, cognitive, and physical symptoms.

22.07.2025 Depression

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