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image Image There are many aspects of Parkinson’s disease (PD) that can intensify the caregiver burden (e.g., impaired movement, sleep disorders, pain, cognitive impairment, etc.).

Perceived caregiver burden as Parkinson’s disease advances

There are many aspects of Parkinson’s disease (PD) that can intensify the caregiver burden

22.02.2025 Parkinson’s Disease

image Image An analysis published in 2020, and including indirect costs, estimated that the total annual economic cost of PD will exceed $79 billion by 2037 in the US alone.

The predicted burden of Parkinson’s disease in the USA up to 2037

An analysis published in 2020, and including indirect costs, estimated that the total annual economic cost of PD will exceed $79 billion by 2037 in the US alone

22.02.2025 Parkinson’s Disease

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The data shown on the illustration come from an analysis of US public and private administrative claims data, which estimated a prevalence of PD in the US of approximately 1 million people, equating to a total cost of $51.9 billion in 2017.{{3}} As shown on the illustration, slightly more than half of this cost was indirect, including non-medical costs, absenteeism, and disability payments.{{3}} Worldwide prevalence of PD is estimated to be around 10 million in 2024{{4,5}}, suggesting substantial indirect costs globally.

The indirect economic burden of Parkinson’s in the USA

In Parkinson’s disease, indirect costs make up a considerable proportion of the overall cost, and can be greater than the direct costs

22.02.2025 Parkinson’s Disease

image Image A real-world, multinational study has shown that the economic burden of Parkinson’s disease (PD) increases as the disease progresses. The main factors that drove healthcare costs were the direct cost of hospitalization and medication costs, and indirect costs. Therefore, treatments to slow or halt PD progression would have substantial economic value to the world.

The economic burden of Parkinson’s disease in the USA, Europe, and Japan by disease stage

A real-world, multinational study has shown that the economic burden of Parkinson’s disease (PD) increases as the disease progresses

22.02.2025 Parkinson’s Disease

image Image (Definitions and cut-offs for early- and late- onset Parkinson’s disease

Definitions and cut-offs for early- and late- onset Parkinson’s disease

Historically, the terms young-onset and early-onset Parkinson’s disease have been used for research of Parkinson’s disease that presents before the typical age

16.02.2025 Parkinson’s Disease

image Image Clinical symptoms and time course of Parkinson’s disease progression