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The idea of preventing disease progression in a condition that is associated with a substantial burden of morbidity and mortality is a very attractive prospect.

Factors associated with mixed features includes unemployment among others

The composition of the gut microbiome is now thought to influence the pathology of mood disorders including schizophrenia and BD, via the microbiome–gut–brain axis

Many of the different symptoms and behaviours typical of bipolar disorder can be modelled in animal behaviour, such as in rodents.

Patients sometimes feel marginalized or stereotyped due to their diagnosis at some point in their lives

Global prevalence of bipolar spectrum disorders