Index for
slide deck
Introduction
Delirium
Case presentation
The slide details a case study of a patient who developed delirium after experiencing stroke.
Delirium
Delirium is a medical condition characterized by acute-onset deficits in attention and other aspects of cognition.1 Various terms have been used in the past for this constellation of symptoms, e.g., ‘acute confusional state’, and ‘organic brain syndrome’.1 This inconsiste…
The history of delirium
As shown on the slide, the term delirium has been used inconsistently in its history stretching back several centuries.1
Definitions
Delirium is a neurocognitive disorder characterized by an acute disturbance in attention, which can be hypo- or hyper-active, or mixed.1
References:
1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders – fifth edition text revision. A…
Epidemiology and risk factors
Epidemiology and risk factors
Delirium and stroke
Delirium is common in stroke, and is associated with poorer outcomes for the patient.2,3 However, the pathogenesis of delirium is poorly understood and thought to involve a multitude of interacting factors which increase the risk of a person experiencing delirium.1
Refere…
Occurrence of delirium in acute stroke
This study followed 141 people after stroke and compared the usefulness of different methods for diagnosing delirium.1 The results, as shown on the slide, show delirium is a common occurrence after stroke, and usually presents within the first 72 hours after stroke.1 Alth…
Pathology of delirium
As outlined on the slide, there are many risk factors which can predispose a person to experiencing delirium.1 Because there is such a complex network of predisposing and precipitating factors, it is often difficult to assign a specific cause of delirium in a patient.1 Th…
Risk factors for post-stroke delirium
Given the negative effects of delirium on the outcomes of stroke, predicting the risk of a person after stroke of developing delirium is a valuable clinical ambition.1,5 One such tool has been developed that included age, stroke severity and subtype, and the presence of i…
Prognosis
Prognosis
Prognosis of delirium in stroke
Although common in people after stroke, the effect of delirium on clinical outcomes in the long term has been poorly studied.2 To address this deficit, the PROPOLIS study (prospective observational Polish study) followed a large group of people (n=682) after stroke, and s…
Post-stroke delirium and cognitive impairment and dementia
People with delirium after stroke appear to be at a higher risk of developing dementia than people who do not experience delirium.1,2 However, delirium and dementia have a complex and interconnected relationship, making studies of the effect of post-stroke delirium on lat…
The relationship between delirium and dementia
Because delirium, cognitive impairment, and dementia appear to be inter-connected, strategies to prevent delirium may help reduce the risk of cognitive decline, or dementia, in older patients.1 As shown on the slide, the multitude of factors involved present many opportun…
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