Stroke is a burdensome condition. In 2019, it was estimated that there were 12.22 million incident cases of stroke and 6.55 million deaths due to stroke. This slide deck discusses the epidemiology and burden of stroke and the epidemiology and impact of neurobehavioral consequences of stroke.

This slide deck was developed by Akin Ojagbemi, MBBS, PhD, MSc, NIHR, University of Ibadan, Nigeria, and Professor Christopher Chen, National University of Singapore, and Director of the Memory Aging and Cognition Centre, Singapore, in collaboration with Cambridge (a division of Prime, Cambridge, UK).

Index for
slide deck

Introduction

Epidemiology and global impact
Epidemiology and global impact
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The neurobehavioural consequences of stroke
The neurobehavioural consequences of stroke

Depending on the severity and the location within the brain of the stroke pathology,4 the damage caused by a stroke can lead to severe neurobehavioural consequences, including neuropsychiatric symptoms (depression, anxiety, apathy, and fatigue), delirium, and cognitive im…

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The burden of stroke

The burden of stroke
The burden of stroke
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The global burden of stroke
The global burden of stroke

Stroke is common across the world, and increased substantially between 1990–2019.2 The greatest rates of stroke burden are seen in low-income countries.2 In order to combat these increases, and halt the increases in the prevalence of stroke worldwide, effective primary pr…

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Disability weights associated with stroke
Disability weights associated with stroke

Health utility scores, examples of which are shown on the slide, can be generated using many different methods, including:2

  • The standard gamble: individuals are presented with a choice between a certain health state (e.g., the current state), or a gamble with one better …
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Risk factors for stroke
Risk factors for stroke

As outlined on the slide, there are many different risk factors for stroke, many of which overlap and interact with each other.1,2

References:
1. US Centre for Disease Control. https://www.cdc.gov/stroke/risk_factors.htm. Accessed July 2023.

2. GBD 2019 Stroke Collaborato…

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Risk factors for stroke from Global Burden of Disease survey
Risk factors for stroke from Global Burden of Disease survey

Data from the Global Burden of Disease survey 2019 have been used to model the burden of stroke, and the risk factors for stroke globally.1 In 2019, the leading risk factors contributing to stroke risk and combined disability-adjusted life years (DALYs) were hypertension,…

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Impact of stroke risk factors
Impact of stroke risk factors

Data from the Global Burden of Disease surveys have been used to model the global, regional, and national burden of stroke and its risk factors, between 1990–2019.1 The analysis also modelled disability-adjusted life years (DALYs) due to the various risk factors of stroke…

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Delirium after stroke

Delirium after stroke
Delirium after stroke
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Prevalence of delirium after stroke
Prevalence of delirium after stroke

As well as acute-onset deficits in attention and other aspects of cognition, people with delirium often also experience altered arousal – ranging from reduced responsiveness to hypervigilance and severe agitation.1,2 Delirium can also include psychosis; i.e., symptoms of …

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Impact of delirium after stroke
Impact of delirium after stroke

Delirium is common in stroke, and is associated with poorer outcomes for the patient.1,3 As well as delirium, attenuated delirium or sub-syndromal delirium after stroke has been studied, and may be a useful indicator of risk of cognitive impairment after stroke.5 In the s…

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Modifiable risk factors for delirium after stroke
Modifiable risk factors for delirium after stroke

After stroke, people are particularly likely to have one or more of the known risk factors for stroke: cognitive impairment, visual impairment, infection, and dehydration.2-4 This study followed 141 patients after stroke, screening twice daily for post-stroke delirium thr…

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