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Mechanisms of association between epilepsy and comorbidity

This illustration outlines the different mechanisms linking epilepsy with comorbidities, including chance associations, causal pathways, resultant effects, shared risk factors, and bidirectional relationships.

28.11.2025 Epilepsy
image Image The physical and social exposome in brain health and dementia across the lifespan
The physical and social exposome in brain health and dementia across the lifespan

Social and physical exposome factors—like poverty, pollution, and inequality—accumulate over time, shaping biological aging and cognitive decline. Through inflammation and cellular stress, these exposures drive neurodegeneration, highlighting the need for longitudinal, integrative research.

12.11.2025 Alzheimer’s Disease
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The accumulated burden of epilepsy-related stigma
05.11.2025 Epilepsy
image Image Diagram showing central and peripheral factors contributing to brain insulin resistance in schizophrenia
Central and peripheral causes of brain insulin resistance in schizophrenia

Central and peripheral causes of brain insulin resistance in schizophrenia

24.10.2025 Schizophrenia
image Image Diagram of insulin signalling in the brain and its effects on neurons and glucose metabolism.
Brain insulin action in relation to peripheral and central outcomes
24.10.2025 Schizophrenia
image Image Infographic illustrating causes of metabolic dysfunction in schizophrenia and associated outcomes such as cardiometabolic disease, brain changes, and reduced quality of life
Causes and consequences of metabolic dysfunction in schizophrenia
24.10.2025 Schizophrenia

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