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Diagnostic tools for epilepsy comorbidities

The figure presents key diagnostic tools used to assess common comorbidities in people with epilepsy. For depression, recommended instruments include the NDDI-E, PHQ-9, BDI-II, and NDDI-E-Y. Anxiety can be evaluated using the GAD-7, EASI, and brEASI. General mental health in children and adolescents is assessed with the SDQ. Developmental disorders and autism may be screened using the ASQ, mCHAT, and SCQ.

28.11.2025 Epilepsy
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Classification of seizures and epilepsies

The figure illustrates the ILAE framework for classification of the epilepsies and to determine different levels of the condition.
Clinicians use different types of diagnostic tools to determine different levels of the condition: (1) the type of seizures, (2) the type of epilepsy, and (3) the epilepsy syndrome.

28.11.2025 Epilepsy
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Self-limited focal epilepsies of childhood

Self-limited focal epilepsies of childhood (SeLFEs) are a group of conditions occurring without a known cause in children who appear cognitively and neurologically normal and have no significant structural brain lesion.

28.11.2025 Epilepsy
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ILAE updated seizure classification (2025)

The figure illustrates the classification of seizures according to the ILAE classification. There are three main classes of seizure – focal, unknown, and generalized – within which there are many different types.

28.11.2025 Epilepsy
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The probability of seizure recurrence

The figure illustrates the probability of seizure recurrence following a first, second, and third unprovoked seizure over long-term follow-up. The study was based on a single-centre surveillance system that was based on hospital admissions, referral for EEG, neurology, or epilepsy clinics for patients who had recently identified seizures.

28.11.2025 Epilepsy
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Risk of recurrent seizure after first unprovoked seizure

The figure shows the cumulative risk of seizure recurrence following a first unprovoked seizure over a 10-year period.

28.11.2025 Epilepsy

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