Alzheimer’s disease (AD) has a significant impact on society – in terms of impaired abilities and quality of life, healthcare costs, caregiver burden, lost earnings, and premature deaths. This slide deck discusses the epidemiology and burden of AD and highlights topics as prevalence of dementia, burden of AD and the assessment scales for the quality of life and resource utilization in dementia.

This slide deck has been developed by Joseph Therriault, PhD, McGill University, Montréal, Québec, Canada; and Professor Serge Gauthier, McGill University, Montréal, Québec, Canada, in collaboration with Cambridge (a division of Prime, Cambridge, UK).

Index for
slide deck

Introduction

Epidemiology and burden
Epidemiology and burden
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Prevalence of dementia

Prevalence of dementia
Prevalence of dementia
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Prevalence of dementia
Prevalence of dementia

References:
1. Alzheimer’s Disease International. Dementia facts and figures. Available at: https://www.alzint.org/about/dementia-facts-figures/. Accessed 2 November 2023.

2. Alzheimer’s Association. What is dementia? Available at: https://www.alz.org/alzheimers-dementia/w…

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Prevalence of Alzheimer’s disease increases with age
Prevalence of Alzheimer’s disease increases with age

The National Institute on Aging-Alzheimer’s Association (NIA-AA) workgroup recently published a research framework which defined AD by neuropathological or biomarker evidence of amyloid-b plaques and tau tangles, rather than clinical symptoms.1 They then aimed to address …

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Projected increase in the prevalence of Alzheimer’s disease dementia
Projected increase in the prevalence of Alzheimer’s disease dementia

In 2011, the largest ever demographic generation in the US, known as the baby-boom generation, started to reach age 65.3 As a result of this generation, the number of Americans aged 85 and above is expected to dramatically increase over the coming years.4 Additionally, th…

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Burden of AD

Burden of AD
Burden of AD

People living with dementia live with the disease for a long time, and therefore, spend a long time living with disability and depending on caregivers.2 As a result, this significantly contributes to the public health impact of the disease.2,5 Cost of care can be divided …

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Dementia has a significant impact on society
Dementia has a significant impact on society

People living with dementia live with the disease for a long time, and therefore, spend a long time living with disability and depending on caregivers.2 As a result, this significantly contributes to the public health impact of the disease.2,5 Cost of care can be divided …

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Number of deaths related to Alzheimer’s disease is rising
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The burden of AD dementia increases throughout its course
The burden of AD dementia increases throughout its course

Global function denotes the overall function of an individual and includes cognitive functions, behaviour, and ability to perform activities of daily living (ADLs).7 As AD progresses, the impact on the three domains reduces global function, and increased caregiver burden.…

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Caregiver burden
Caregiver burden

For caregivers of people living with dementia, the role involves helping the patient with acts of daily living (i.e., household chores, shopping, preparing meals, managing finances, arranging medical appointments, maintaining personal hygiene), administering medications, …

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Caregiver burden is multi-faceted
Caregiver burden is multi-faceted

As AD progresses, people living with dementia become increasingly dependent on the caregiver.2 The current healthcare system is highly reliant on informal unpaid caregivers, many of whom are also socioeconomically and medically vulnerable.4,5 As a result, family and careg…

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Demographics of caregivers for patients with dementia
Demographics of caregivers for patients with dementia

The majority of dementia caregivers live with the patient in the community,1 with 60% of caregivers being married, living with a partner, or in a long-term relationship.1,5 Among primary caregivers of people living with dementia, more than half take care of their parents.…

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