Slide Decks on Depression
Depression is a broad and heterogeneous diagnosis. The many symptoms of depression cause clinically significant distress or impairment in social, occupational, or other important areas of functioning. The severity of the disorder is determined by both the number and severity of symptoms, as well as the degree of functional impairment.
Major Depressive Disorder (MDD) often has a remitting and relapsing course, and symptoms may persist between episodes. Where possible, the key goal of an intervention should be complete relief of symptoms (remission), which is associated with better functioning and a lower likelihood of relapse. Clinical guidelines recommend several approaches to the treatment of MDD: Pharmacotherapy (e.g., antidepressants), which can include combination therapy of more than one medication. Psychological therapy (e.g., cognitive–behavioral therapy) can be given alongside pharmacotherapy.
Our educational slide decks are designed to include a comprehensive range of subjects, from the definition of MDD to its global prevalence, its comorbidities, prognosis, and treatment options. All our materials are developed by experts in the field and are available for free download and use in your presentations.
Definitions and Diagnosis
This slide deck explains fundamental concepts and definitions related to depression, including signs and symptoms, differential diagnosis, and commonly used screening and rating instruments. Go to the slide deck.
Epidemiology and Burden
This slide deck presents the essential components of the epidemiology and burden of Major Depressive Disorder (MDD), summarizing global patterns and societal impacts. Go to the slide deck.
Neurobiology and Aetiology
This slide deck introduces the neurobiology and aetiology of major depressive disorder (MDD), focusing on the genetic, biological, environmental, and psychological factors that shape its development. Go to the slide deck.
Course, Natural History and Prognosis
Major depressive disorder (MDD) is characterized by discrete episodes of changes in affect, cognition, and neurovegetative functions. Depression often has a remitting and relapsing course. Go to the slide deck.
Comorbidity
The various comorbidities of Major Depressive Disorder (MDD) negatively impact patients’ quality of life. This slide deck discusses in detail the presence of comorbidity in MDD. Go to the slide deck.
Treatment Principles
This slide deck includes comprehensive slides and figures illustrating the treatment principles of Major Depressive Disorder (MDD), such as pharmacotherapy and non-pharmacological therapies. Go to the slide deck.
Articles on Depression
Depression is a clinically heterogeneous disorder. The many symptoms of depression are varied, and can include emotional, cognitive, and physical symptoms that cause clinically significant distress or impairment in social, occupational, or other important areas of functioning.
Read and download our articles, written by experts, which introduce the latest advances in research in depression and the future clinical practice related to Major Depressive Disorder (MDD).
- Treatment-Resistant Depression (TRD) – definition, clinical manifestation, and evidence-based treatment
Treatment-resistant depression (TRD) represents a significant clinical challenge, affecting approximately 30% of individuals with major depressive disorder (MDD) who fail to respond to at least two adequate antidepressant trials. - Precision psychiatry in depression treatment: mechanism-based subtyping
This article reviews the shift towards more personalised care by integrating biological and clinical profiles to guide mechanism-based, targeted interventions across psychiatric conditions. - Polygenic Scores in Psychiatry: The Example of Depression
This article discusses the latest advances in psychiatric genetics, focusing on MDD, the use of PRS in research, and potential future clinical practice applications.
Watch the Videos on Depression
MDD is most frequently characterized by relapses and recurrences. The symptoms of depression may persist between episodes. The various symptoms of depression have a negative impact on many aspects of the patient’s life. Listen to our experts discuss diverse topics in depression research, uncovering different aspects of this clinically heterogeneous disorder.
Polygenic Scores in Psychiatry
Dr. Jasmina Mallet explains the latest research in psychiatric genetics, emphasizing the role of Polygenic Risk Scores (PRS) in psychiatry.
Depression in the Workplace
In this video, Prof. Dr. David Nutt describes the burden of depression in the workplace.
The Heterogeneity of Depression
In this video, Professor Dr. Brenda Penninx discusses the heterogeneity of major depressive disorder, with specific reference to immunometabolic depression.
Download Illustrations & Figures on Depression
Explore our comprehensive library of downloadable illustrations, designed to improve your understanding of scientific and medical concepts and enhance your presentations. We have numerous illustrations and explanations on topics such as Noradrenergic and Specific Serotonergic Antidepressants, the Effects of a Noradrenaline Antagonist, Specific Noradrenaline Re-Uptake Inhibitors, and much more.
3D Brain Atlas
In the 3D Brain Atlas you can see many of the brain’s structures from a 360 degree viewpoint, make various sagittal incisions through the brain, read more about the structures, and download images of the brain that you can use in your own presentations.
Some areas of the brain appear to be particularly associated with depression. Biological factors contributing to depression, especially in terms of brain structure and function, include:
- Hippocampal atrophy
- Thinner cortical grey matter in the orbitofrontal cortex, anterior and posterior cingulate and insula
- Overactivation of the amygdala under emotional exposure
